Advances in the science and treatment of alcohol use disorder
Although recent research has expanded understanding of alcohol use disorder, more research is needed to identify the neurobiological, genetic and epigenetic, psychological, social, and environmental factors most critical in the etiology and treatment of this disease. Implementation of this knowledge in clinical practice and training of health ...
Evidence-Based Pharmacotherapies for Alcohol Use Disorder
Pathologic alcohol use affects more than 2 billion people and accounts for nearly 6% of all deaths worldwide. There are three medications approved for the treatment of alcohol use disorder by the US Food and Drug Administration (FDA): disulfiram, naltrexone (oral and long-acting injectable), and acamprosate. Of growing interest is the use of anticonvulsants for the treatment of alcohol use ...
Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review
Alcohol use disorder (AUD), a problematic pattern of alcohol use accompanied by clinically significant impairment or distress, is present in 14% of U.S. adults, though only 7% of affected individuals are seen in an alcohol treatment facility. ... Additional research is needed to identify more efficacious medications and to define the optimal ...
Overview of Alcohol Use Disorder
Alcohol is regularly consumed throughout most of the world, including by nearly half the U.S. population age 12 or older. Heavy drinking, which is also common, contributes to multiple adverse medical, psychiatric, and social outcomes and more than 140,000 deaths annually in the United States. It is the major risk factor for alcohol use disorder (AUD), whose current U.S. prevalence is 11% ...
Prevention, screening, and treatment for heavy drinking and alcohol use
Heavy drinking and alcohol use disorder (AUD) are major public health concerns. Alcohol consumption is prevalent worldwide. In 2016, 2·4 billion people (33% of the global population) were current drinkers. 1 In the United States, specifically, the prevalence of alcohol use disorder (AUD) and high-risk drinking in adults has increased substantially over the past ten years. 2 One in eight U.S ...
Advances in the science and treatment of alcohol use disorder
Only a small percent of individuals with alcohol use disorder contribute to the greatest societal and economic costs ().For example, in the 2015 National Survey on Drug Use and Health survey (total n = 43,561), a household survey conducted across the United States, 11.8% met criteria for an alcohol use disorder (n = 5124) ().Of these 5124 individuals, 67.4% (n = 3455) met criteria for a mild ...
Incorporating harm reduction into alcohol use disorder treatment and
For many years, complete abstinence from alcohol consumption was viewed as the most effective way to recover from alcohol use disorder (AUD) and was a primary outcome of AUD treatment. A large body of evidence, however, suggests that treatment and recovery strategies that reduce heavy alcohol consumption and alcohol-related consequences without ...
Alcohol use disorders
Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent mental disorders globally, especially in high-income and upper-middle-income countries; and are associated with high mortality and burden of disease, mainly due to medical consequences, such as liver cirrhosis or ...
Research
Research on medications in development for treatment of alcohol use disorder. NIAAA Data Archive The NIAAA data archive is a data repository that houses and shares human subjects data generated by NIAAA-funded research.
Evidence-based models of care for the treatment of alcohol use disorder
It is well recognized that alcohol use disorders (AUD) have a damaging impact on the health of the population. According to the World Health Organization (WHO), 5.3% of all global deaths were attributable to alcohol consumption in 2016 [].The 2016 Global Burden of Disease Study reported that alcohol use led to 1.6% (95% uncertainty interval [UI] 1.4-2.0) of total DALYs globally among females ...
Alcohol use disorders
Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent mental disorders globally, especially in high-income and upper-middle-income countries; and are associated with high mortality and burden of disease, mainly due to medical consequences, such as liver cirrhosis or ...
Alcohol Use Disorder and Depressive Disorders
Alcohol use disorder (AUD) and depressive disorders are among the most prevalent psychiatric disorders and co-occur more often than expected by chance. ... Key future directions include studies to understand the heterogeneity of both AUD and depressive disorders, research on novel treatment approaches to enhance outcomes, and better ...
An integrated multimodal model of alcohol use disorder ...
Lifetime incidence of alcohol use disorder (AUD) is as high as 29-30% 1,2, with alcohol use being a leading cause of death [3 million worldwide in 2016 or 5.3% of all deaths worldwide 3].
Alcohol Research: Current Reviews
Alcohol Use Disorder and Dementia: A Review. Natalie M. Zahr . 14 March 2024. ... 2024 marks the 50th anniversary of Alcohol Research: Current Reviews (ARCR), an open-access, peer-reviewed journal published by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) ...
A randomized trial testing digital medicine support models for mild-to
Alcohol use disorder (AUD) can be conceptualized along a spectrum of risk, with appropriate interventions dependent on an individual's risk of progressing to severe AUD over the lifetime 5.
Understanding alcohol use disorders and their treatment
According to the National Institute on Alcohol Abuse and Alcoholism (NIAAA), 6.2 percent of adults in the United States aged 18 and older had alcohol use disorder. 1 For example, a government survey revealed that about one in five individuals aged 12 to 20 were current alcohol users and about two in five young adults, aged 18 to 25, were binge ...
Age-related differences in the effect of chronic alcohol on cognition
While most of our knowledge on the effects of alcohol on the brain and cognitive outcomes is based on research in adults, several recent reviews have examined the effects of alcohol on the brain ...
Treatment of Alcohol Use Disorder
Alcohol use disorder (AUD) is a disease that occurs when alcohol significantly impairs an individual's health and functioning. The severity of AUD ranges from mild to severe, and symptoms have the potential for recurrence and remission. No matter how severe the disorder is, individuals can benefit from treatment. Diagnosis.
Epidemiology of Recovery From Alcohol Use Disorder
Almost one-third of the U.S. population meets alcohol use disorder (AUD) criteria on a lifetime basis. This review provides an overview of recent research on the prevalence and patterns of alcohol-related improvement and selectively reviews nationally representative surveys and studies that followed risk groups longitudinally with a goal of informing patients with AUD and AUD researchers ...
Understanding Alcohol Use Disorder
It encompasses the conditions that some people refer to as alcohol abuse, alcohol dependence, alcohol addiction, and the colloquial term, alcoholism. Considered a brain disorder, AUD can be mild, moderate, or severe. Lasting changes in the brain caused by alcohol misuse perpetuate AUD and make individuals vulnerable to relapse.
Alcohol use disorder
Alcohol use disorder is a pattern of alcohol use that involves problems controlling your drinking, being preoccupied with alcohol or continuing to use alcohol even when it causes problems. ... Some research studies indicate that having bariatric surgery may increase the risk of developing alcohol use disorder or of relapsing after recovering ...
The substance use disorder treatment gap among US college students
Drug Alcohol Depend Rep. 2024 Aug 30:12:100279. doi: 10.1016/j.dadr.2024.100279. ... 3 Institute for Social Research, University of Michigan, Ann Arbor, MI, ... Background: Substance use and substance use disorders (SUD) are prevalent among college students. Information about the gap between substance use treatment need versus treatment receipt ...
Prevalence of Alcohol Use, High-Risk Drinking, and DSM-IV Alcohol Use
Alcohol use and specifically high-risk drinking, which often leads to alcohol use disorder (AUD), are significant contributors to the burden of disease in the United States and worldwide. 1-7 High-risk drinking and AUD are important risk factors for morbidity and mortality from fetal alcohol spectrum disorders, 8 hypertension, 9 cardiovascular ...
Association of education attainment, smoking status, and alcohol use
Previous research on the risk of dementia associated with education attainment, smoking status, and alcohol use disorder (AUD) has yielded inconsistent results, indicating potential heterogeneous treatment effects (HTEs) of these factors on dementia risk. Thus, this study aimed to identify the important variables that may contribute to HTEs of these factors in older adults.
Alcohol Use Disorder
Alcohol is the most commonly used substance in the United States, with 84% of people 18 and older reporting lifetime use, according to data from the 2022 National Survey on Drug Use and Health. Alcohol use exists along a spectrum from low risk to alcohol use disorder (AUD). The intervening category, known as risky drinking, includes heavy drinking as well as binge drinking.[1] AUD is a chronic ...
Is self-compassion a protective factor for addictions? Exploring its
Self-compassion has been generally recognized as a protective psychological factor against mental illnesses. However, its protective value against addictions remained unclear. To address this research gap, the current study explores the associations between self-compassion and both alcohol use disorder [AUD] and gambling disorder [GD] tendencies under the framework of self-compensation model ...
The use of baclofen as a treatment for alcohol use disorder: A clinical
Alcohol use disorder (AUD) is a brain disorder associated with high rates of mortality and morbidity worldwide. Baclofen, a selective gamma-aminobutyric acid-B (GABA-B) receptor agonist, has emerged as a promising drug for AUD. The use of this drug remains controversial, in part due to uncertainty regarding dosing and efficacy, alongside concerns about safety. To date there have been 15 ...
Do You Have an Alcohol Use Disorder and Want Treatment?
This research study is investigating if eating a ketogenic diet (including high fat, low carbohydrate shakes) will have an effect on symptoms of alcohol withdrawal and on brain function in patients with alcohol use disorder undergoing inpatient treatment of alcohol detoxification. You may be eligible for this research study if you:
Epidemiology of Recovery From Alcohol Use Disorder
Almost one-third of the U.S. population meets alcohol use disorder (AUD) criteria on a lifetime basis. This review provides an overview of recent research on the prevalence and patterns of alcohol-related improvement and selectively reviews nationally representative surveys and studies that followed risk groups longitudinally with a goal of informing patients with AUD and AUD researchers ...
Alcohol Use Disorder and Depressive Disorders
Introduction. Psychiatric disorders, such as anxiety and mood disorders, commonly co-occur with alcohol use disorder (AUD). Depressive disorders are the most common psychiatric disorders among people with AUD.1 The co-occurrence of these disorders is associated with greater severity and worse prognosis than either disorder alone,2,3 including a heightened risk for suicidal behavior.4 This ...
COMMENTS
Although recent research has expanded understanding of alcohol use disorder, more research is needed to identify the neurobiological, genetic and epigenetic, psychological, social, and environmental factors most critical in the etiology and treatment of this disease. Implementation of this knowledge in clinical practice and training of health ...
Pathologic alcohol use affects more than 2 billion people and accounts for nearly 6% of all deaths worldwide. There are three medications approved for the treatment of alcohol use disorder by the US Food and Drug Administration (FDA): disulfiram, naltrexone (oral and long-acting injectable), and acamprosate. Of growing interest is the use of anticonvulsants for the treatment of alcohol use ...
Alcohol use disorder (AUD), a problematic pattern of alcohol use accompanied by clinically significant impairment or distress, is present in 14% of U.S. adults, though only 7% of affected individuals are seen in an alcohol treatment facility. ... Additional research is needed to identify more efficacious medications and to define the optimal ...
Alcohol is regularly consumed throughout most of the world, including by nearly half the U.S. population age 12 or older. Heavy drinking, which is also common, contributes to multiple adverse medical, psychiatric, and social outcomes and more than 140,000 deaths annually in the United States. It is the major risk factor for alcohol use disorder (AUD), whose current U.S. prevalence is 11% ...
Heavy drinking and alcohol use disorder (AUD) are major public health concerns. Alcohol consumption is prevalent worldwide. In 2016, 2·4 billion people (33% of the global population) were current drinkers. 1 In the United States, specifically, the prevalence of alcohol use disorder (AUD) and high-risk drinking in adults has increased substantially over the past ten years. 2 One in eight U.S ...
Only a small percent of individuals with alcohol use disorder contribute to the greatest societal and economic costs ().For example, in the 2015 National Survey on Drug Use and Health survey (total n = 43,561), a household survey conducted across the United States, 11.8% met criteria for an alcohol use disorder (n = 5124) ().Of these 5124 individuals, 67.4% (n = 3455) met criteria for a mild ...
For many years, complete abstinence from alcohol consumption was viewed as the most effective way to recover from alcohol use disorder (AUD) and was a primary outcome of AUD treatment. A large body of evidence, however, suggests that treatment and recovery strategies that reduce heavy alcohol consumption and alcohol-related consequences without ...
Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent mental disorders globally, especially in high-income and upper-middle-income countries; and are associated with high mortality and burden of disease, mainly due to medical consequences, such as liver cirrhosis or ...
Research on medications in development for treatment of alcohol use disorder. NIAAA Data Archive The NIAAA data archive is a data repository that houses and shares human subjects data generated by NIAAA-funded research.
It is well recognized that alcohol use disorders (AUD) have a damaging impact on the health of the population. According to the World Health Organization (WHO), 5.3% of all global deaths were attributable to alcohol consumption in 2016 [].The 2016 Global Burden of Disease Study reported that alcohol use led to 1.6% (95% uncertainty interval [UI] 1.4-2.0) of total DALYs globally among females ...
Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent mental disorders globally, especially in high-income and upper-middle-income countries; and are associated with high mortality and burden of disease, mainly due to medical consequences, such as liver cirrhosis or ...
Alcohol use disorder (AUD) and depressive disorders are among the most prevalent psychiatric disorders and co-occur more often than expected by chance. ... Key future directions include studies to understand the heterogeneity of both AUD and depressive disorders, research on novel treatment approaches to enhance outcomes, and better ...
Lifetime incidence of alcohol use disorder (AUD) is as high as 29-30% 1,2, with alcohol use being a leading cause of death [3 million worldwide in 2016 or 5.3% of all deaths worldwide 3].
Alcohol Use Disorder and Dementia: A Review. Natalie M. Zahr . 14 March 2024. ... 2024 marks the 50th anniversary of Alcohol Research: Current Reviews (ARCR), an open-access, peer-reviewed journal published by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) ...
Alcohol use disorder (AUD) can be conceptualized along a spectrum of risk, with appropriate interventions dependent on an individual's risk of progressing to severe AUD over the lifetime 5.
According to the National Institute on Alcohol Abuse and Alcoholism (NIAAA), 6.2 percent of adults in the United States aged 18 and older had alcohol use disorder. 1 For example, a government survey revealed that about one in five individuals aged 12 to 20 were current alcohol users and about two in five young adults, aged 18 to 25, were binge ...
While most of our knowledge on the effects of alcohol on the brain and cognitive outcomes is based on research in adults, several recent reviews have examined the effects of alcohol on the brain ...
Alcohol use disorder (AUD) is a disease that occurs when alcohol significantly impairs an individual's health and functioning. The severity of AUD ranges from mild to severe, and symptoms have the potential for recurrence and remission. No matter how severe the disorder is, individuals can benefit from treatment. Diagnosis.
Almost one-third of the U.S. population meets alcohol use disorder (AUD) criteria on a lifetime basis. This review provides an overview of recent research on the prevalence and patterns of alcohol-related improvement and selectively reviews nationally representative surveys and studies that followed risk groups longitudinally with a goal of informing patients with AUD and AUD researchers ...
It encompasses the conditions that some people refer to as alcohol abuse, alcohol dependence, alcohol addiction, and the colloquial term, alcoholism. Considered a brain disorder, AUD can be mild, moderate, or severe. Lasting changes in the brain caused by alcohol misuse perpetuate AUD and make individuals vulnerable to relapse.
Alcohol use disorder is a pattern of alcohol use that involves problems controlling your drinking, being preoccupied with alcohol or continuing to use alcohol even when it causes problems. ... Some research studies indicate that having bariatric surgery may increase the risk of developing alcohol use disorder or of relapsing after recovering ...
Drug Alcohol Depend Rep. 2024 Aug 30:12:100279. doi: 10.1016/j.dadr.2024.100279. ... 3 Institute for Social Research, University of Michigan, Ann Arbor, MI, ... Background: Substance use and substance use disorders (SUD) are prevalent among college students. Information about the gap between substance use treatment need versus treatment receipt ...
Alcohol use and specifically high-risk drinking, which often leads to alcohol use disorder (AUD), are significant contributors to the burden of disease in the United States and worldwide. 1-7 High-risk drinking and AUD are important risk factors for morbidity and mortality from fetal alcohol spectrum disorders, 8 hypertension, 9 cardiovascular ...
Previous research on the risk of dementia associated with education attainment, smoking status, and alcohol use disorder (AUD) has yielded inconsistent results, indicating potential heterogeneous treatment effects (HTEs) of these factors on dementia risk. Thus, this study aimed to identify the important variables that may contribute to HTEs of these factors in older adults.
Alcohol is the most commonly used substance in the United States, with 84% of people 18 and older reporting lifetime use, according to data from the 2022 National Survey on Drug Use and Health. Alcohol use exists along a spectrum from low risk to alcohol use disorder (AUD). The intervening category, known as risky drinking, includes heavy drinking as well as binge drinking.[1] AUD is a chronic ...
Self-compassion has been generally recognized as a protective psychological factor against mental illnesses. However, its protective value against addictions remained unclear. To address this research gap, the current study explores the associations between self-compassion and both alcohol use disorder [AUD] and gambling disorder [GD] tendencies under the framework of self-compensation model ...
Alcohol use disorder (AUD) is a brain disorder associated with high rates of mortality and morbidity worldwide. Baclofen, a selective gamma-aminobutyric acid-B (GABA-B) receptor agonist, has emerged as a promising drug for AUD. The use of this drug remains controversial, in part due to uncertainty regarding dosing and efficacy, alongside concerns about safety. To date there have been 15 ...
This research study is investigating if eating a ketogenic diet (including high fat, low carbohydrate shakes) will have an effect on symptoms of alcohol withdrawal and on brain function in patients with alcohol use disorder undergoing inpatient treatment of alcohol detoxification. You may be eligible for this research study if you:
Almost one-third of the U.S. population meets alcohol use disorder (AUD) criteria on a lifetime basis. This review provides an overview of recent research on the prevalence and patterns of alcohol-related improvement and selectively reviews nationally representative surveys and studies that followed risk groups longitudinally with a goal of informing patients with AUD and AUD researchers ...
Introduction. Psychiatric disorders, such as anxiety and mood disorders, commonly co-occur with alcohol use disorder (AUD). Depressive disorders are the most common psychiatric disorders among people with AUD.1 The co-occurrence of these disorders is associated with greater severity and worse prognosis than either disorder alone,2,3 including a heightened risk for suicidal behavior.4 This ...